Workshops
Events for March 12, 2026
Measuring proteins with photoelectric silicon biosensors
Dr. Marcie Black Advanced Silicon GroupProtein sensing is where the rubber hits the road in biology. Hence, measuring protein concentrations is important for many applications, including point-of-care testing, bio and pharma manufacturing, food production, bioweapons detection, and agriculture. The field of biosensing has made great progress and is about to enter a more mature stage that will greatly improve our lives. In this talk, we review the market for biosensing. Then we focus on ASG’s photo-electric enzyme-linked immunosorbent assay (ELISA) that uses the change in photocurrent of a weakly passivated photovoltaic cell to measure changes in the surface recombination velocity as a result of the presence/absence of proteins on the diode’s surface. Since we use silicon wafers and perform an electrical measurement, we can make use of the semiconductor industry’s ability to pack many tests onto the same chip, thus creating a cost-efficient, multiplexed test that measures the concentration of many different proteins simultaneously. We will explore the mechanism of the operation of the sensors. In addition, we will present results showing the response of the sensor when exposed to an organic molecule of interest.Marcie Black is CEO and co-founder of Advanced Silicon Group (ASG). Dr. Black brings to the company expertise in building strong teams, managing development projects, patents, IP strategy, encouraging a healthy company culture, cost modeling, and running a startup. In addition, Dr. Black has a strong technical background in the areas of electronic materials, optics, semiconductors, solar cells/photovoltaics, batteries, renewable energy, nanotechnology, device design, and opto-electronics. Prior to founding ASG, Marcie was the President and co-founder of Bandgap Engineering, which focused on lowering the cost of solar electricity through black silicon or silicon nanowire solar cells. Before joining Bandgap, Marcie was a technical staff member at Los Alamos National Laboratory and worked on a variety of nanotechnology and optical systems. She began at Los Alamos National Labs as a prestigious Director’s Funded Post Doc, developing organic and nano solar cells. Marcie has a Ph.D. from MIT in Electrical Engineering, under the supervision of Institute Professor, Mildred Dresselhaus. Prior to her Ph.D. work, Marcie was a device engineer at Motorola, where she was on a small team responsible for combining non-volatile memory and logic onto the same chip. She improved the manufacturing yields by working with the process engineer to improve silicide formation. In 2009, she was awarded an R&D 100 award for her contributions to work at LANL. Marcie was also honored as one of the ten “Women-to-Watch in 2010” by Mass High Tech. Marcie has published over 30+ papers, given two TedxTalks, and has a long list of patents issued.Register for this event.